Cancer

Bridging Research and Hope

CONTACT

wesparkhealth@uwindsor.ca

PROGRAM SUMMARY:

Cancer remains one of the most significant health challenges facing our communities. As one of WE-SPARK's three strategic research pillars, Cancer Research brings together researchers, clinicians, learners, and community partners committed to advancing prevention, detection, treatment, survivorship, and supportive care. Through WE-SPARK's programs, funding opportunities, research support services, and collaborative network, cancer researchers are able to build partnerships, accelerate discovery, and translate knowledge into meaningful improvements for patients and families in Windsor-Essex and beyond.

Related Programs:

Nucleus Cores:

Ashtanga yoga for women with breast cancer: A feasibility study

Identifying a genetic signature that predicts progression of colorectal cancer to invasive cancer

NKR-P1A-mediated immunosurveillance in colorectal cancer

Implementing and evaluating a compassionate community intervention to improve the holistic health, social support, and healthcare utilization of the LGBTQ+ people experiencing cancer

Validating the use of mobile technology to identify potential neurocognitive change in cancer patients undergoing chronic, immune based therapies

Design of probes specific for PSMA or NAALADaseL1 to identify early stage neuroendocrine-like prostate cancer

Cancer Rehabilitation Services for Radiation Oncology Patients

Investigating a novel Cyclin-Tuberin mediated cell size checkpoint that protects against cancer

Structure-based drug discovery targeting ubiquitin-specific protease 9X for cancer treatment

Identifying early stage neuroendocrine-like prostate cancer

Artificial Intelligence in the Radiation Treatment Planning Process for Cancer

Designing Drugs: Computational Modelling to Select Target Molecules for Autoimmune Disease and Anti-Cancer Applications

Barriers to cancer patient clinical trial enrollment and develop interventional education program

Cancer Cachexia Research

Design and Synthesis of the Acetal-Free Analogues of the Tn Antigen for the Treatment of Lung Cancer

A Matter of Timing: Circadian Clock Regulation of Intestinal Healing and Cancer

Novel Cell Cycle Regulation in Triple Negative Breast Cancer

Dissecting Novel Mechanisms Regulating Breast Cancer Stem Cells

Next-Generation Bioelectronic Sensors for Post-Partum Breast Cancer Detection

Characterizing a Novel Model of Inducible Skeletal Muscle Inflammation

Nothing About Us Without Us: Co-Designing a Youth Engagement Framework for Adolescent and Young Adult Cancer Care in Regional Settings

Decoding NK Cell Immune Reconstitution Patterns in CMV Reactivation After Allogeneic Stem Cell Transplantation

Revealing Hidden Determinants of Cancer Risk: An Integrated Occupational and Reproductive Cancer Registry in Autoworkers with a Focus on Young Women and Post-Partum Breast Cancer

Strengthening Cancer Care Through Early Psychosocial Intervention: A Proactive Social Work Engagement Model at a Regional Cancer Centre

Assessing Medical Isotope Needs and Opportunities in Windsor-Essex and Beyond

Circadian Nutrition to Prevent Colorectal Cancer

Validating New Avenues in Characterization and Treatment of Pediatric Glioblastoma

From Oncology to Primary Care: Determinants of Endocrine Therapy Persistence in Breast Cancer Survivorship

Cancer immunoevasion via an inhibitory nk cell receptor

Dissecting the Biology of Disease Progression and Drug Resistance in Glioblastoma

Circadian nutrition to prevent colorectal cancer

Mapping Tumour Suppressor Partners during Cell Proliferation using BioID

An Implementation/Effectiveness Feasibility Study to Assess a Home-Based Rehabilitation Exercise Program Prior to Hematopoietic Stem Cell Transplantation in a Community Setting

Integration of a Multidisciplinary Program for the Prevention of Venous Thrombosis in Outpatients with Cancer at a Large Community Hospital

Mass Spectrometry Imaging Platform for Revealing Spatial Metabolic Alterations in Cancer Tissues

New Detection Strategies For Post-partum Breast Cancer Based On Organic Mixed Ionic-electronic Conducting Polymers

Hematopoietic abnormalities and impact on innate immune functions in cancer

Surface-Enhanced Raman Spectroscopy for Detecting Modified Nucleosides as Cancer Biomarkers

Study of Automated Cancer Diagnosis Through Medical Imaging

Targeting Mechanisms of Drug Resistance and Tumour Recurrence in Glioblastoma

Disparities of health that impact outcomes for patients with multiple myeloma

Evaluation and Impact of an Oral Health Education Program in a Mental Health Inpatient Setting

Design and Evaluation of Novel 3D Bioinformatic Tools to Explore Cell Cycle-Targeting Approaches Against Neuroblastoma

CA-125: Towards a new label for ovarian cancer

Examining the Effect of Exercise on Sphingolipid Metabolism in a Genetic Model of Colorectal-Induced Cachexia

CDK4/6 Inhibitors as Immune Modulators in HR+/HER2- Breast Cancer

Establishing a Biomarker Discovery Platform to Track Progression to Treatment Resistant Neuroendocrine Prostate Cancer

Identifying biomarkers of therapeutically targetable tumour-immune cell interactions in small cell lung cancer

MIR142 in Non-Hodgkin Lymphoma

Expansion of the Clinical Trials Navigator (CTN) Program with staged introduction of the navigator program to demonstrate benefit to availability of the CTN program

pHerapeutics: Modulating the tumour microenvironment restores immunosurveillance, eliminates cancer's "home-field" advantage, and potentiates therapies

Evaluating the association between travel burden and effective cancer care on overall survival and quality of life with novel chemotherapy satellite site

A novel translational pipeline for the treatment of multiple myeloma

Improving outcomes in glioblastoma treatment: Implantable therapeutic polymer composites for targeted drug delivery

Design, fabrication, and testing of 3D printed micro-fluidic devices for exploring the culture of human tumour based organoids, and to alter the tumour microenvironment

Shed lights on SUN1 for cancer treatments

Exploring the process of receiving pediatric cancer care in Windsor Essex region through the lived experiences of youths living with cancer, parents, and healthcare providers

Automated detection of brain metastases using machine learning

Defining relative cell cycle lengths in mixed cell populations

Role of Cyclin-Like Proteins in Regulating the Regenerative Balance in the Liver; Implications in Fatty Liver Disease and Hepatocellular Carcinoma

Automated Matching of HER2 Positive Breast Cancer and Sarcoma Patients in Ontario, Canada Using Artificial Intelligence

Role of Cyclin-Like Proteins in Regulating the Regenerative Balance in the Liver; Implications in Fatty Liver Disease and Hepatocellular Carcinoma

Migrant Worker's Experience of Critical Illness in Windsor-Essex County

Using Virus-like Particles to Deliver Protein Therapeutics for Glioblastoma Treatment

Boron Concentration in Normal Organs and Tumors of Companion Animals: A Preclinical Trial for Boron Neutron Capture Therapy

Neurosurgery Endovascular Robotic Platform

A Novel High-Resolution Micromachined Ultrasonic Technology in Dermatology for Skin Cancer Detection

Translational Platform to Dissect the Biology of Relapse for Triple Negative Breast Cancer

Exploring the adoption of T-DM1 in adjuvant therapy for residual disease following neoadjuvant chemotherapy in HER-2 positive breast cancer

Use of Digital Mobile Technology for Rapid Assessment of Treatment Induced Cognitive Deficits in Multiple Myeloma Patients

Targeting the Cell Cycle Mediator Spy1 in Treatment-Resistant Neuroendocrine Prostate Cancer

Investigation of the fertility preservation education provided to cancer patients at Windsor Regional Hospital

Head and Neck Cancer Radiation Treatment Planning Peer Review Quality Assurance Outcome in Windsor Ontario: A Single Institution Experience

The risks and benefits of perioperative steroids in the surgical treatment of malignant brain tumour

Drug delivery vehicle to transport drugs across the blood-brain barrier to target Glioblastoma

Role of Cyclin-Like Proteins in Regulating Regenerative Balance in the Liver

Automated Organ Segmentation with Deep Learning Algorithm

Immunosurveillance of breast cancer by innate immune cells

Early identification of Neuroendocrine-like prostate cancer using Near-Infrared Light

The Temporal Dynamics of Physical Activity on Quality of Life in Primary Brain Tumour

Comparing Anthracycline Based on Non-Anthracycline Based Chemotherapy: Is an Anthracycline-based Regimen Necessary in Triple-negative Breast Cancer?

Brain Metastasis HSRT Outcome in Windsor Ontario: A Single Institution Experience

Immunotherapy for the Treatment of Advanced Non-Small Cell Lung Cancer: A Single Centre Retrospective Study

Sexual Orientation and Gender Identity Data Collection in Cancer Care Settings: A Single-Centre Retrospective Review

CML STOP: Prospective study of patients with CML who reach a unique criteria for stopping TKI

Stage migration of patients presenting to WRH with Colorectal cancer during the Covid pandemic

Expanding our investigations into the significance of grade in prognosis in patient with Triple Negative Breast Cancer

Evaluating Conjugated Polymer Nanoparticles as a New Molecular Platform for the Selective Treatment of Glioblastoma

Realizing Boron Neutron Capture Therapy at the University of Windsor

Characterizing novel antibodies specific for cell-surface 9-O-acetyl-sialic acid residues

Real World Experience – Stopping Study in Chronic Myeloid Leukemia

Late Accelerator Unique and Selective Targeting of Cdk Activity in Aggressive Carcinomas

Understanding mechanism of action: Combined computational and structural biology studies to determine small molecule effects on protein dynamics and function

Multi-user in vivo animal imaging system

Targeting Cyclin-Like Proteins in Human Glioma

Unique and Selective Targeting of Cdk Activity in Aggressive Carcinomas

Targeting Cell Cycle Checkpoints in Glioma

Brain Tumour Organoid Screening Model to Optimize Therapeutic Options for Patients with Glioblastoma

Role of Tuberin in Cell Cycle Progression through G2/M

The timing of cancer: an investigation of the circadian clock and photoperiod on tumorigenesis in the APCmin mouse

Dr. Dora Cavallo-Medved

Dr. Andrea Cervi

Dr. Elizabeth Fidalgo da Silva

Dr. Bre-Anne Fifield

Dr. Laurie Freeman

Dr. Vikas Garg

Dr. Rasna Gupta

Dr. Caroline Hamm

Dr. Scott Harroun

Dr. Josée Jarry

Dr. Sindu Kanjeekal

Dr. Phillip Karpowicz

Dr. Sahar Khan

Dr. Anna Kozarova

Dr. Matthew Krause

Dr. Swati Kulkarni

Dr. Dorota Lubanska

Dr. Drew Marquardt

Emma Mineau

Dr. Alioune Ngom

Dr. Ming Pan

Dr. Kathy Pfaff

Dr. Lisa Porter

Dr. Munir Rahim

Dr. Jody Ralph

Dr. Simon Rondeau-Gagné

Dr. Luis Rueda

Dr. Ayman Sayyed

Dr. Ken Schneider

Daniel Scurto

Dr. Andrew Swan

Dr. Joanne Tay

Dr. Yufeng Tong

Dr. John Trant

Dr. Panayotis Vacratsis

Dr. Nick Vukotic

Dr. Indryas Woldie

Dr. Junaid Yousuf

Today, cancer patients live longer because of advancements stemming from research. WE-SPARK is excited to build and strengthen our current local cancer research program to better serve the patients of the Lake Erie-St. Clair region. And we are dedicated to making a difference in the fight against cancer. Donations made to WE-SPARK Health Institute are designated to our Grants Program. With your help, these grants will help grow our research community, ignite new discoveries, address gaps in healthcare needs, generate and disseminate knowledge, spark collaborations and improve the health of our community. Thank you to all our supporters, we couldn't do it without you!


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Cancer

Cancer

Bridging Research and Hope

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