This study explores the development and feasibility of a home-based exercise rehabilitation program for patients undergoing hematopoietic cell transplantation (HCT). Frailty before transplant is common and associated with worse survival outcomes and quality of life, yet limited data exist on how structured pre-habilitation could improve physical resilience. Through patient interviews and surveys, this project will co-design a rehabilitation program tailored to the needs and barriers experienced by HCT patients. A pilot implementation will assess program feasibility in terms of recruitment, adherence, and preliminary physical outcomes. Insights from the study are expected to inform larger-scale trials and support the integration of personalized pre-habilitation into cancer care.

This project has the potential to improve strength, function, and transplant readiness in patients undergoing HCT by creating a patient-centered exercise program that is accessible and sustainable. It will also generate early evidence to support broader implementation of pre-habilitation strategies in community cancer care.