The Students Igniting Vaccine Confidence Program engages a multidisciplinary and diverse team of postsecondary students to work collaboratively to design activities, translate information, and educate all members of our regional community about COVID-19 vaccines. The program aims to achieve four main objectives: 1) identify and understand drivers of both vaccine confidence and hesitancy, particularly in students and young adults; 2) focus on the unique perspective of racially and ethnically diverse younger populations; 3) develop and implement evidence-based practices that effectively promote vaccine confidence by addressing personal, social and physical barriers to vaccine knowledge and trust; and 4) leverage community partners and empower early adopters to inspire trust, ensure equitable access, and foster greater COVID-19 vaccine confidence.