Targeting the root cause of Rheumatoid Arthritis

Targeting the root cause of Rheumatoid Arthritis

Targeting the root cause of Rheumatoid Arthritis: Preventing the HLA-antigen interaction responsible for Rheumatoid Arthritis


Dr. John Trant

University of Windsor

 

The project plans to design new chemical probes that bind extremely tightly to immune system receptors that initiate an immune response to collagen and other antigens. By blocking these receptors, we can potentially develop a new therapy to relieve the burden of rheumatoid arthritis. These probes will also help colleagues in the field explore the molecular underpinnings of this disease.

Related Programs:
Nucleus Cores:

FUNDER:

Arthritis Society

GRANT DURATION:

2018-2026

 

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